Naltrexone Protocol for Cancer


Naltrexone Protocol

Jake Ames, MD, HMD & Douglas G. Mitchell, Ph.D., D. Univ.

This is a protocol for low dose naltrexone (LDN). You need prescriptions for Naltrexone

Instructions using compounded tablets

You need a compounding pharmacist.

The first prescription should be for 21 1.5 mg tablets, and 90 4.5 mg tablets. Subsequent prescriptions are only for 4.5 mg tablets. The pharmacist will prepare these tablets.

You always take LDN at bedtime.

Week 1: Take 1.5 mg tablets at bedtime.
Week 2: Take 2 1.5 mg tablets at bedtime.
Week 3 and thereafter: Take 4.5 mg tablets each day for life.

Instructions using 50 mg tablets

Naltrexone is mainly sold as 50 mg tablets. These are available off the shelf. If a compounding pharmacist is not available or too expensive, buy 50 mg tablets.
Crush the tablet with a mortar and pestle or use the back of a spoon on a plastic cutting board to crush the tablet into a very fine powder.

Put the Naltrexone powder into a glass jar with a screw-on lid.  The jar is big enough to hold 50 ml of water. 
Add 50 ml of distilled water or reversed osmosis water into the glass jar.  Your water should contain close to zero parts per million dissolved solids, (ppm).  Measure this with a total dissolved solutes (TDS) meter. The resulting mixture contains 1 mg/mL Naltrexone.

Shake the bottle thoroughly, and then use a 5 mL syringe to withdraw 1.5 mL (1.5 mg), 3.0 mL or 4.5 mL as required.

Make sure that you shake the closed jar real thoroughly each time you draw out the Naltrexone.

Side Effects

We usually do not see any side effects.  Rarely, patients may have some mild nausea at the 4.5 mg dosage. The patient then needs to decrease the dosage to 3.5 mg. This  usually works to eliminate any nausea.  A few weeks later, return to a 4.5 mg dose.  Patients now usually tolerate this dosage.

© 2017 Jake Ames, MD, HMD  All Rights Reserved